Under OFFIS' scientific leadership one of the first Grid projects for SMEs has been launched. The project funded by BMBF called "BIS-Grid" will make usable Grid technologies for the integration of decentralized enterprise informatics systems. Distributed or Grid computing is functioning according to a simple principle: What is too complex for a single one, can all of a sudden and easily be accomplished by many. Enormous data amounts, that are no exception in scientific research, can be processed by a single supercomputer or in scanty measures by many small home PCs. Projects like "seti@home" are well known and jump first to the mind if we think about Grid technologies. However, the newly started BMBF project "BIS-Grid" will try to demonstrate that these technologies not only can be usefully applied to distributed computing performances in complex scientific domains such as astrophysics or climatology, but also can be used for enterprise-specific software intergration based on their capacities with regard to co-ordination, security and reliability. As one of the first projects for the commercial implementation of Grid technologies the researchers want to substantially expand the application potential for Grid technologies and to bring them together with the world of Enterprise Application Integration (EAI) and Service-Oriented Architectures (SOA). Both technologies have a lot in common since they are focused on integration issues within heterogeneous environments. In addition Grid technologies are covering the resources and SOA from the application levels. BIS-Grid is aiming to achieve progress on the conceptual as well as the technical level for a "horizontal Service-Grid" for application in enterprise informatics systems. On the conceptual level new forms of co-operation and new enterprise models will be developed. On the technical level the Business Process Execution Language (BPEL) for Grid Services will be implemented. The achievement of this target will be evaluated in practice by means of two user scenarios with scientific partners. The project results will therefore provide an essential contribution to the practical use of Grid technologies in the area of enterprise informatics systems integration. The lasting continuity of the developed services and concepts will be supported by the use of the technologies that are developed in BMBF's D-Grid initiative, by the development of new enterprise models and by the co-operation with other D-Grid projects. In the D-Grid initiative BMBF since 2005 is supporting the use of Grid technologies that enable the efficient use of computer resources for complex calculations and the processing of enormous amounts of data. In this second D-Grid call another 9 projects from over 50 submitted proposals will be selected to receive funding, next to BIS-Grid. Unter the scientific leadership of Prof. Dr. Wilhelm Hasselbring from the OFFIS Informatics Institute, a consortium consisting of the scientific partners OFFIS (co-ordination), Research Centre Juelich, PC2 of the Paderborn University and the TU Berlin as well as the industrial partners CADsys (Chemnitz), CeWe Color (Oldenburg), KIESELSTEIN (Chemnitz) and Siemens AG (Paderborn) will be awarded a three-year funding of over two million euro by BMBF.